Introduction:-As the world moves towards new discoveries, inventions, lifestyles have also been drastically altered, the homo sapiens as we know it has evolved, in every field of life . However, when it comes to food, there has always been the risk of dangers and the intake of chemically synthesized material, which has become a blessing and a consequence that we have to pay for modernism. However, the demand for safer and fresher products still remains an issue. As the world's population increases every second, the need for more food supplies continues to grow. Due to this increased demand, food preservation becomes a necessity. And this is where the word food additives begins. Food additives have received a great deal of attention from food scientists around the world and are now the most visited areas of science. As the world is starting to find more and more additives, many global consumers feel harassed by their use. It has still become a major concern of critics; however, the tug of war is still ongoing between the two juries. FOOD ADDITIVES: - The chemical substance that is used to be added to food (University of Alabama A and M and Auburn). The following are the main objectives of food additives:-Maintain or increase the nutritional value of food that has undergone harsh treatment, destroyed during processing. For example, vitamin C, vitamin B, iodine and vitamin D. To increase the keeping quality of food by adding antioxidants, colors and natural flavors. To increase the processing quality or ease of processing. However, food laws enacted by several agencies have problems now, with occasional congressional interventions continuing to threaten the FDA, which has the public's soul at its center of attention... middle of paper... Rats si they refused to swim and their immobility was observed. It was also observed that rats became antisocial after taking a high dose of tartrazine, their amount of time in social interaction significantly decreased. The forced swimming test was conducted to understand depression in rats (Raghavandra et al. 2000). They were observed to exhibit higher levels of immobility, a potential indicator of depression-like behavior, a reaction to stress. (Sanchez and Meier, 1997). Tartrazine intake also caused a depressive response and was evidenced in children who also showed clinical depression. , migraines and sleep disorders (Rowe and Rowe, 1994) (November et al. 1992) tartrazine and benzoates have been reported to cause unusual reactions in the central nervous system causing headaches, hyperactivity, learning difficulties and depression.