Few human experiences are as miserable as dealing with being alone; perhaps because isolation is so easily recognized and dwelled on when you are without friends to distract you from the troubles of life. Let us now consider isolation in its most extreme form and reflect on what such abject solitude might do to man. This is the fate of Doctor Frankenstein and the monster in Mary Shelly's Frankenstein. Frankenstein is the story of how one man's experiment has the unintended consequence of making Frankenstein and his creation, the Monster, completely isolated from the rest of humanity: the creator of the unnatural monster dares not tell his story for fear that, because of its punitive guilt, the horrible being itself shares neither kinship nor experience with anyone. This point will guide our discussion of how Frankenstein and the Monster were initially segregated from humanity due to seeking knowledge that neither should have in the context of their lives. Then the creation scene will be discussed in detail to show how Frankenstein's perversion of natural, biologically driven birth adds a dimension to that separation, an incompatibility with human nature, that makes their isolation complete. After that, the final outcome of the isolation of man and monster will be described as an inevitable fall since they cannot overcome this misalignment because it mires them in personal loneliness, they cannot overcome themselves and they cannot seek help because their isolation it is so complete, that is, their situation is truly monstrous and beyond reproach. The discussion will conclude by using a broader perspective to explore the true depths of isolation these unhappy characters feel and what lessons about our experiences with loneliness we gain from understanding them. Clearly, Frankenstein is a departure from previous men, as is he. , Ingolstadt's most applied natural philosopher, who first formulated the life-giving machinations. This creation of a being in a way that skips maternal birth in a paroxysm of biological asymmetry hurts him because he will never be able to internalize the stark fact of having released such a demon into the world. This internal discord prevents him from forming any real relationship again and leads him to attempt a solo suicidal pilgrimage to end the suffering his creation causes him. As for the artificially created being, it is by definition a departure from all life that came before because it was artificially created. This alone does not mean that it is excluded from human understanding, but by the fact that it is also a grotesque monster and is therefore cursed to alert the natural primal flight response before it can beg man's more reasonable evolved responses to listen. his great intelligence. Following this one-sided torment, the Monster decides to embark on a hateful life dedicated to punishing the human race, guilty only of misunderstandings, which ultimately lead him to the madness of pain. So how did these come about?