Based on the definition, venomics is the study of the proteome of venoms. Venomics is a research program initiated by the International Society of Toxicology. The aim of this program is to analyze and examine the genomic background of venomous animals using new technologies based on genomics, proteomics and transcriptomics. In the course of its studies, venomics has shown us that venomous animals can be dangerous and deadly but sometimes they can be a treasure of substances and molecules that can be useful for the discovery of drugs and the development of strategies against poisoning (Menez , 2006). special glandular organs capable of secreting toxic substances, these substances are called poisons. Poisons have specific functions for animals, for example some discharge their poisons into the environment to protect themselves from enemies, other times the poison is mixed with digestive juices playing an important role in nourishing the animal, and in still others In some cases are used by animals as a sort of defense or attack by binding-stinging other animals or humans. An animal is defined as poisonous when it has the ability to inoculate its own poison. Poisonous animals come from lower areas such as Protozoa, Arthropods, Molluscs, Coelenterates and Vertebrates including reptiles, fish and amphibians (Bale and Danielsson, 1908). The reasons why man is so interested in the study of poisons are 3 reasons. First, they can be an important source of tools to study essential biological systems such as the peripheral nervous system, blood coagulation, the hormonal system, homeostasis, the immune system and the cardiovascular system (Menez, 2002). Secondly, they can constitute a fundamental source for the development of... half of the article... 279-295.3. Juan J. Calvetea, Sanza, L, Angulob, Y. (2009). Poisons, venomics, antivenoms. Functional genomics and proteomics. 583 (11), 1736-1743,4. Junghanss, T, Bodio, M. (2006). Medically important venomous animals: biology, prevention, first aid and clinical management. Clinical infectious diseases. 43(10), 1309-1317,5. King, G. (2013). Poisons into drugs: translating venom peptides into therapeutic agents. Special technical feature. 44(3), 13-15.6. Menez, A. (2006). Venomics' or: the venom systems genome project. Available: http://www.atheris.ch/Downloads/2006%20Venomics%20Editorial-Toxicon%20PM16460774.pdf. Last accessed May 18, 2014.7. Ménez, A, Stöcklin, R, Mebs, D. (2006). Venomics” or: The Venomous Systems Genome Project. Available: http://www.toxinomics.org/CONCO/pdf/articles/Poster%20Venomics%20Noumea%20061019.pdf. Last access May 18th 2014.