In particular, the methods focus on the evaluation of different interventions and their development. Qualitative methods are useful in developing its quantitative tools, and quantitative research informs qualitative research. The method that integrates and explains primary qualitative data is the quantitative method. Both qualitative and quantitative methods have equal and parallel intensities. Furthermore, it reviews published studies with combined approaches in qualitative and quantitative research. Mixed methods resonate with the complexity of palliative care venturing into the research and employed applications needed. The research involves the collection and analysis of data with integrated findings using qualitative and quantitative approaches. It is recommended that both approaches develop and evaluate the complex interventions needed for palliative care research. Overall, research requires a deep understanding of research processes and its perspective. Research Questions After extensive reading, the research questions focused on: Do palliative care researchers need innovations or creative approaches in the current generation of research? They realize the multidimensional spheres of increasingly diversified and dispersed nature