The issue discussed by Ron, Williams and Dickens concerns the conditions under which the use of human subjects in medical research is justified. Roy and his colleagues believe that the health, lives, and dignity of people involved as subjects in medical research must be protected for the research to be ethically justifiable. Roy and his colleagues believe that four conditions must be met for a medical research or clinical trial to be ethically justified, the research must be scientifically adequate; the rights of human subjects protected; doctors obtain informed consent from patients; patients should be informed about randomization. First, Roy et al. stated that adequate preliminary testing in animal models must be carried out before human subjects are used in a clinical trial. Medical research or clinical trials with human subjects must comply with the principle of the scientific method. Medical professionals and researchers involved in this research must have appropriate qualifications. Second, Roy and his colleagues proposed that in clinical trials, human subjects should be subjected to pr...