One of the most common diarrheal diseases is amoebiasis, caused by the parasitic protist Entamoeba histolytica which affects 50 million people and causes 100,000 deaths per year worldwide. One of the most common diarrheal diseases is amoebiasis, caused by the parasitic protist Entamoeba histolytic. Transmitted via the fecal-oral route, ingestion of the infected cystic form occurs through contaminated food and water. Random Agent E. histolytica is a protozoan parasite responsible for a disease called amoebiasis. Several species of protozoa of the genus Entamoeba colonize humans, but not all are associated with the disease. E. histolytica is well recognized as a pathogenic amoeba, associated with intestinal and extraintestinal infections. E. histolytica goes through two life cycles: a cyst that can survive harsh conditions, such as the human stomach and small intestine; the cystic form transmits the disease. The trophozoite that fights host infection by invading epithelial cells. Occasionally trophozoites may be transmitted during sexual intercourse. actual infection of the host by invading the host epithelium that survives in harsh environments as well as in tA the trophozoite is an active form or a feeding form of a protozoan, especially a parasite, as opposed to the resting or reproductive form. Trophozoites migrate to the large intestine where they live and multiply through binary fission. E.histlytica lives and multiplies in the human body as a trophozoite. A trophozoite is an active form or feeding form of a protozoan, especially a parasite, as opposed to the resting or reproductive form. Trophozoites migrate to the large intestine where they live and multiply through binary fission.E. histolytica trophozoites begin p...... middle of paper ......contaminated water.• Public education about the possibility of transmitting the disease through sexual contact Consider fecal screening for family members and institutional contacts. Fecal screening is recommended for traveling companions of a confirmed case. Confirmed carriers also need to be treated. Environmental measures to control disease transmission focus on: • Protecting public water supplies from fecal contamination • Investigating the food preparation practices of any affected food establishments. In case of multiple cases, public health measures involve: • Confirmation by laboratory results • Undertaking an epidemiological investigation to determine the source of infection and common mode of transmission. • Take appropriate measures to eliminate any common vehicles of transmission, such as contaminated food or water, to prevent further cases.